Article
The myocardial infarction associated CDKN2A/CDKN2B locus on chromosome 9p21 is associated with stroke independently of coronary events in patients with hypertension.
Journal of hypertension - 1 Apr 2009
Wahlstrand Björn, Orho-Melander Marju, Delling Lotta, Kjeldsen Sverre, Narkiewicz Krzysztof, Almgren Peter, Hedner Thomas, Melander Olle
Abstract excerpt
OBJECTIVE: We tested whether two single-nucleotide polymorphisms (SNPs) (rs2383207 and rs10757278), previously strongly associated with myocardial infarction, are independently associated with stroke and coronary events in patients with hypertension. METHODS: The Nordic Diltiazem study compared the effects of calcium antagonist and beta-blocker or diuretic-based antihypertensive treatment on cardiovascular events...
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