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Article

Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis.

Chemistry & biology - 28 May 2010

Pierrel Fabien, Hamelin Olivier, Douki Thierry, Kieffer-Jaquinod Sylvie, Mühlenhoff Ulrich, Ozeir Mohammad, Lill Roland, Fontecave Marc

Abstract excerpt

Yeast ubiquinone or coenzyme Q(6) (Q(6)) is a redox active lipid that plays a crucial role in the mitochondrial electron transport chain. At least nine proteins (Coq1p-9p) participate in Q(6) biosynthesis from 4-hydroxybenzoate (4-HB). We now show that the mitochondrial ferredoxin Yah1p and the ferredoxin reductase Arh1p are required for Q(6) biosynthesis, probably for the first hydroxylation of the pathway....

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PMID: 20534343
DOI: 10.1016/j.chembiol.2010.03.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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