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Article

Variation in the relative copy number of the TLR7 gene in patients with systemic lupus erythematosus and healthy control subjects.

Arthritis and rheumatism - 1 Oct 2007

Kelley James, Johnson Martin R, Alarcón Graciela S, Kimberly Robert P, Edberg Jeffrey C

Abstract excerpt

OBJECTIVE: To determine whether there is an increase in the number of TLR7 gene copies in patients diagnosed as having systemic lupus erythematosus (SLE) and whether gene amplification influences the autoantibody profiles in SLE patients, as has recently been reported in the BXSB/Yaa mouse model of lupus. METHODS: We used a modified real-time quantitative polymerase chain reaction protocol to calculate the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17907191
DOI: 10.1002/art.22916

Genes

TLR7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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