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Article

Dynamic single-cell network profiles in acute myelogenous leukemia are associated with patient response to standard induction therapy.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2010

Kornblau Steven M, Minden Mark D, Rosen David B, Putta Santosh, Cohen Aileen, Covey Todd, Spellmeyer David C, Fantl Wendy J, Gayko Urte, Cesano Alessandra

Abstract excerpt

PURPOSE: Complete response to induction chemotherapy is observed in approximately 60% of patients with newly diagnosed non-M3 acute myelogenous leukemia (AML). However, no methods exist to predict with high accuracy at the individual patient level the response to standard AML induction therapy. EXPERIMENTAL DESIGN: We applied single-cell network profiling (SCNP) using flow cytometry, a tool that allows a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20525753
DOI: 10.1158/1078-0432.CCR-10-0093
PMCID: PMC3385931

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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