Article
Transmembrane domain length variation in the evolution of major histocompatibility complex class I genes.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1991
Crew M D, Filipowsky M E, Neshat M S, Smith G S, Walford R L
Abstract excerpt
The fifth exons of major histocompatibility complex (MHC) class I genes encode a transmembrane domain (TM) that is largely responsible for class I antigen cell-surface expression usually through conventional hydrophobic amino acid-membrane interactions or, less often, through phosphatidylinositol...
Topics
- Animals
- Base Sequence
- Biological Evolution
- Cell Membrane
- Chromosome Deletion
- Cricetinae
- DNA
- Exons
- Genes, MHC Class I
- Genetic Variation
- Histocompatibility Antigens Class I
- Mesocricetus
- Mice
- Molecular Sequence Data
- Oligonucleotide Probes
- Peromyscus
- Polymerase Chain Reaction
- Rats