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Article

Association of common polymorphisms in the fractalkine receptor (CX3CR1) with obesity.

Obesity (Silver Spring, Md.) - 1 Jan 2011

Sirois-Gagnon Dave, Chamberland Annie, Perron Stéphanie, Brisson Diane, Gaudet Daniel, Laprise Catherine

Abstract excerpt

The inflammatory component in obesity is now well established. The CX3CR1 gene encodes the fractalkine (CX3CL1) receptor and has two coding single-nucleotide polymorphisms, V249I and T280M, linked to a lower risk of other inflammatory diseases such as coronary artery disease (CAD) and asthma. To determine whether CX3CR1 is associated with obesity, we genotyped the V249I and T280M polymorphisms of the CX3CR1 gene...

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Source

Identifiers

PMID: 20523302
DOI: 10.1038/oby.2010.125

Genes

CAD

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Association of common polymorphisms in the fractalkine receptor (CX3CR1) with obesity.PMID 20523302Read ↗

Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease.Semantic proximity Read ↗

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