Article
Interaction analysis of IL-12A and IL-12B gene variants with chronic hepatitis B infection in Tunisian patients.
Immunology letters - 1 Sept 2020
Ben Selma Walid, Laribi Ahmed Baligh, Alibi Sana, Saad Afef, Boukadida Jalel
Abstract excerpt
Given the key role of interleukin-12 (IL-12) in the control of HBV, we investigated the possible correlation between IL-12A rs568408 and IL-12B rs3212227 polymorphisms and the risk of chronic HBV infection in Tunisian population. Two hundred patients with chronic HBV infection and two hundred healthy controls were genotyped using PCR-RFLP. A allele, AA and AG genotypes of IL-12A rs568408 were more represented in...
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