Article
COPI vesicle transport is a common requirement for tube expansion in Drosophila.
PloS one - 9 Apr 2008
Jayaram Satish Arcot, Senti Kirsten-André, Tiklová Katarína, Tsarouhas Vasilios, Hemphälä Johanna, Samakovlis Christos
Abstract excerpt
BACKGROUND: Tube expansion defects like stenoses and atresias cause devastating human diseases. Luminal expansion during organogenesis begins to be elucidated in several systems but we still lack a mechanistic view of the process in many organs. The Drosophila tracheal respiratory system provides an amenable model to study tube size regulation. In the trachea, COPII anterograde transport of luminal proteins is...
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