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Article

Understanding the role of PknJ in Mycobacterium tuberculosis: biochemical characterization and identification of novel substrate pyruvate kinase A.

PloS one - 24 May 2010

Arora Gunjan, Sajid Andaleeb, Gupta Meetu, Bhaduri Asani, Kumar Pawan, Basu-Modak Sharmila, Singh Yogendra

Abstract excerpt

Reversible protein phosphorylation is a prevalent signaling mechanism which modulates cellular metabolism in response to changing environmental conditions. In this study, we focus on previously uncharacterized Mycobacterium tuberculosis Ser/Thr protein kinase (STPK) PknJ, a putative transmembrane protein. PknJ is shown to possess autophosphorylation activity and is also found to be capable of carrying out...

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Identifiers

PMID: 20520732
DOI: 10.1371/journal.pone.0010772
PMCID: PMC2875399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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