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Article

UDP-galactose 4' epimerase (GALE) is essential for development of Drosophila melanogaster.

Disease models & mechanisms - 1 Jan 2000

Sanders Rebecca D, Sefton Jennifer M I, Moberg Kenneth H, Fridovich-Keil Judith L

Abstract excerpt

UDP-galactose 4' epimerase (GALE) catalyzes the interconversion of UDP-galactose and UDP-glucose in the final step of the Leloir pathway; human GALE (hGALE) also interconverts UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine. GALE therefore plays key roles in the metabolism of dietary galactose, in the production of endogenous galactose, and in maintaining the ratios of key substrates for glycoprotein and...

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Source

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Identifiers

PMID: 20519568
DOI: 10.1242/dmm.005058
PMCID: PMC2931539

Genes

GALE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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UDP-galactose 4' epimerase (GALE) is essential for development of Drosophila melanogaster.PMID 20519568Read ↗

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