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Article

Oxidative stress contributes to outcome severity in a Drosophila melanogaster model of classic galactosemia.

Disease models & mechanisms - 1 Jan 2013

Jumbo-Lucioni Patricia P, Hopson Marquise L, Hang Darwin, Liang Yongliang, Jones Dean P, Fridovich-Keil Judith L

Abstract excerpt

Classic galactosemia is a genetic disorder that results from profound loss of galactose-1P-uridylyltransferase (GALT). Affected infants experience a rapid escalation of potentially lethal acute symptoms following exposure to milk. Dietary restriction of galactose prevents or resolves the acute se...

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Identifiers

PMID: 22773758
DOI: 10.1242/dmm.010207
PMCID: PMC3529341

Genes

GALT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22773758-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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