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Article

Prognostic significance of immunohistochemical phenotypes in patients treated for high-grade cervical intraepithelial neoplasia.

BioMed research international - 1 Jan 2013

Origoni Massimo, Parma Marta, Dell'Antonio Giacomo, Gelardi Chiara, Stefani Chiara, Salvatore Stefano, Candiani Massimo

Abstract excerpt

Strong evidence exists that the host's immune system plays a crucial role for the development of human papillomavirus-related cervical premalignant and malignant lesions. In particular, effective cell-mediated immunity (CMI) promotes spontaneous infection clearance and cancer precursors regression in healthy subjects, while immunosuppressed individuals are more likely to experience infection persistence, cervical...

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Identifiers

PMID: 24455729
DOI: 10.1155/2013/831907
PMCID: PMC3878632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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