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Article

Aldehyde dehydrogenase (ALDH) activity does not select for cells with enhanced aggressive properties in malignant melanoma.

PloS one - 20 May 2010

Prasmickaite Lina, Engesaeter Birgit Ø, Skrbo Nirma, Hellenes Tina, Kristian Alexandr, Oliver Nina K, Suo Zhenhe, Maelandsmo Gunhild M

Abstract excerpt

BACKGROUND: Malignant melanoma is an exceptionally aggressive, drug-resistant and heterogeneous cancer. Recently it has been shown that melanoma cells with high clonogenic and tumourigenic abilities are common, but markers distinguishing such cells from cells lacking these abilities have not been identified. There is therefore no definite evidence that an exclusive cell subpopulation, i.e. cancer stem cells...

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Identifiers

PMID: 20505780
DOI: 10.1371/journal.pone.0010731
PMCID: PMC2874003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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