Article
A longitudinal study of epigenetic variation in twins.
Epigenetics - 16 Aug 2010
Wong Chloe Chung Yi, Caspi Avshalom, Williams Benjamin, Craig Ian W, Houts Renate, Ambler Antony, Moffitt Terrie E, Mill Jonathan
Abstract excerpt
DNA methylation is a key epigenetic mechanism involved in the developmental regulation of gene expression. Alterations in DNA methylation are established contributors to inter-individual phenotypic variation and have been associated with disease susceptibility. The degree to which changes in loci-specific DNA methylation are under the influence of heritable and environmental factors is largely unknown. In this...
Topics
- Child
- Child, Preschool
- DNA Methylation
- Epigenesis, Genetic
- Female
- Genetic Variation
- Genomic Instability
- Humans
- Inheritance Patterns
- Longitudinal Studies
- Male
