Article
Mannose-binding lectin gene (MBL-2) polymorphism in oral lichen planus.
Clinical oral investigations - 1 Oct 2011
Barkokebas Andreza, de Albuquerque T Carvalho Alessandra, de Souza Paulo Roberto Eleutério, Gomez Ricardo Santiago, Xavier Guilherme Machado, Ribeiro Camila Maria Beder, Crovella Sergio, Porter Stephen Ross, Leão Jair Carneiro
Abstract excerpt
TNF-α may be associated with the etiopathogenesis of oral lichen planus (OLP), and it has been suggested that polymorphism of mannose-binding lectin (MBL) increases the in vitro production of TNF- α. The aim of the present study was to assess the relevance of genetic diversity of MBL in OLP. The study sample comprised 90 individuals, 45 OLP patients and 45 healthy volunteers. MBL-2 gene was amplified using...
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