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Article

MicroRNAs and HDAC4 protein expression in the skeletal muscle of ALS patients

31 Jan 2020

Abstract excerpt

AIM: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the progressive degeneration of motor neurons. MicroRNAs are 17 - 27 nucleotide long molecules that regulate post-transcriptional mRNA expression. The aim of this study was to investigate the role of microRNAs in the skeletal muscle of ALS patients and correlate these results with the expression of histone deacetylase 4 (HDAC4)...

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PMID: 32000889
DOI: 10.5414/np301233

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