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Article

Second generation sequencing of the mesothelioma tumor genome.

PloS one - 13 May 2010

Bueno Raphael, De Rienzo Assunta, Dong Lingsheng, Gordon Gavin J, Hercus Colin F, Richards William G, Jensen Roderick V, Anwar Arif, Maulik Gautam, Chirieac Lucian R, Ho Kim-Fong, Taillon Bruce E, Turcotte Cynthia L, Hercus Robert G, Gullans Steven R, Sugarbaker David J

Abstract excerpt

The current paradigm for elucidating the molecular etiology of cancers relies on the interrogation of small numbers of genes, which limits the scope of investigation. Emerging second-generation massively parallel DNA sequencing technologies have enabled more precise definition of the cancer genome on a global scale. We examined the genome of a human primary malignant pleural mesothelioma (MPM) tumor and matched...

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Share to Chromosomes, Human, Pair 21
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 20485525
DOI: 10.1371/journal.pone.0010612
PMCID: PMC2869344

Genes

DPP10
DHFR
NFKB1
NFRKB
PCBD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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