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Article

100 ns molecular dynamics simulations to study intramolecular conformational changes in Bax.

Journal of biomolecular structure & dynamics - 1 Aug 2010

Koshy C, Parthiban M, Sowdhamini R

Abstract excerpt

Bax is a pro-apoptotic member of the widely studied Bcl-2 family of apoptotic proteins. Its function is regulated by anti-apoptotic members of the same family. Bcl-x(L) is one such member, which plays a key role in inhibiting the function of Bax. Recent experimental evidences suggest that intra-molecular conformational changes in the all-helical fold of Bax are necessary for it to be amenable to regulation by...

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Identifiers

PMID: 20476796
DOI: 10.1080/07391102.2010.10507344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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