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Article

Reevaluation of the association of seven candidate genes with blood pressure and hypertension: a replication study and meta-analysis with a larger sample size.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Aug 2012

Takeuchi Fumihiko, Yamamoto Ken, Katsuya Tomohiro, Sugiyama Takao, Nabika Toru, Ohnaka Keizo, Yamaguchi Shuhei, Takayanagi Ryoichi, Ogihara Toshio, Kato Norihiro

Abstract excerpt

To obtain evidence for blood pressure (BP) trait association, we conducted an association study of selected candidate gene variants. In Japan, a total of 19,426 individuals underwent testing for genetic associations with systolic BP (SBP)/diastolic BP (DBP) and 9271 individuals (3460 cases and 5811 controls) underwent testing for genetic associations with dichotomous hypertension. Association with seven notable...

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Source

Identifiers

PMID: 22456346
DOI: 10.1038/hr.2012.43

Genes

DBP
ACE
AGT
ADD1
ADRB2
GNB3
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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