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Article

The gang of four gene regulates growth and patterning of the developing Drosophila eye.

Fly - 1 Jan 2000

Beam Carolyn K, Moberg Kenneth

Abstract excerpt

We report here the identification of a novel complementation group in the fruit fly Drosophila melanogaster named gang of four (gfr). Mutations in gfr disrupt patterns of cell differentiation in the eye and increase eye size through a proliferative mechanism that can be enhanced by a block in apoptosis. gfr mutant cells show several features of deregulated Ras/MAP kinase activity, including reduced expression of...

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Identifiers

PMID: 20473027
DOI: 10.4161/fly.4.2.11890
PMCID: PMC2908041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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