Article
Reevaluation of the 9 compounds reported conclusive positive in yeast Saccharomyces cerevisiae aneuploidy test systems by the Gene-Tox Program using strain D61.M of Saccharomyces cerevisiae.
Mutation research - 1 Jun 1991
Albertini S
Abstract excerpt
The state of aneuploidy test methodology was appraised by the U.S. Environmental Protection Agency in 1986 in analyzing published data. In Saccharomyces cerevisiae 9 chemicals were reported to be conclusive positive for aneuploidy induction in either mitotic or meiotic cells. We reevaluated these...
Topics
- Acetone
- Aneuploidy
- Benomyl
- Benzimidazoles
- Biotransformation
- Carbamates
- Chromosomes, Fungal
- Cyclophosphamide
- Ethyl Methanesulfonate
- Evaluation Studies as Topic
- Methyl Methanesulfonate
- Mitosis
- Mutagenicity Tests
- Mutagens
- Mutation
- Nocodazole
- Saccharomyces cerevisiae
- Tetradecanoylphorbol Acetate