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Article

Additive genetic breeding values correlate with the load of partially deleterious mutations.

Science (New York, N.Y.) - 14 May 2010

Tomkins Joseph L, Penrose Marissa A, Greeff Johan, LeBas Natasha R

Abstract excerpt

The mutation-selection-balance model predicts most additive genetic variation to arise from numerous mildly deleterious mutations of small effect. Correspondingly, "good genes" models of sexual selection and recent models for the evolution of sex are built on the assumption that mutational loads and breeding values for fitness-related traits are correlated. In support of this concept, inbreeding depression was...

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PMID: 20466931
DOI: 10.1126/science.1188013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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