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Article

Inbreeding depression: tests of the overdominance and partial dominance hypotheses.

Evolution; international journal of organic evolution - 1 Apr 2002

Roff Derek A

Abstract excerpt

The two principal theories of the causal mechanism for inbreeding depression are the partial dominance hypothesis and the overdominance hypothesis. According to the first hypothesis, inbreeding increases the frequency of homozygous combinations of deleterious recessive alleles thereby decreasing fitness, whereas the overdominance hypothesis posits that inbreeding increases homozygosity and thus reduces the...

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Identifiers

PMID: 12038534
DOI: 10.1111/j.0014-3820.2002.tb01387.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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