Article
Protein synthesis requirements for nuclear division, cytokinesis, and cell separation in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Jul 1991
Burke D J, Church D
Abstract excerpt
Protein synthesis inhibitors have often been used to identify regulatory steps in cell division. We used cell division cycle mutants of the yeast Saccharomyces cerevisiae and two chemical inhibitors of translation to investigate the requirements for protein synthesis for completing landmark events after the G1 phase of the cell cycle. We show, using cdc2, cdc6, cdc7, cdc8, cdc17 (38 degrees C), and cdc21 (also...
Topics
- Cell Cycle
- Cell Division
- Cell Nucleus
- Cycloheximide
- DNA Replication
- Fungal Proteins
- Genotype
- S Phase
- Saccharomyces cerevisiae
- Trichodermin