Article
Interaction between 5 genetic variants and allergy in glioma risk.
American journal of epidemiology - 1 Jun 2010
Schoemaker Minouk J, Robertson Lindsay, Wigertz Annette, Jones Michael E, Hosking Fay J, Feychting Maria, Lönn Stefan, McKinney Patricia A, Hepworth Sarah J, Muir Kenneth R, Auvinen Anssi, Salminen Tiina, Kiuru Anne, Johansen Christoffer, Houlston Richard S, Swerdlow Anthony J
Abstract excerpt
The etiology of glioma is barely known. Epidemiologic studies have provided evidence for an inverse relation between glioma risk and allergic disease. Genome-wide association data have identified common genetic variants at 5p15.33 (rs2736100, TERT), 8q24.21 (rs4295627, CCDC26), 9p21.3 (rs4977756, CDKN2A-CDKN2B), 11q23.3 (rs498872, PHLDB1), and 20q13.33 (rs6010620, RTEL1) as determinants of glioma risk. The...
