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Article

Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking.

American journal of epidemiology - 1 Sept 2011

Lachance Daniel H, Yang Ping, Johnson Derek R, Decker Paul A, Kollmeyer Thomas M, McCoy Lucie S, Rice Terri, Xiao Yuanyuan, Ali-Osman Francis, Wang Frances, Stoddard Shawn M, Sprau Debra J, Kosel Matthew L, Wiencke John K, Wiemels Joseph L, Patoka Joseph S, Davis Faith, McCarthy Bridget, Rynearson Amanda L, Worra Joel B, Fridley Brooke L, O'Neill Brian Patrick, Buckner Jan C, Il'yasova Dora, Jenkins Robert B, Wrensch Margaret R

Abstract excerpt

Glioma risk has consistently been inversely associated with allergy history but not with smoking history despite putative biologic plausibility. Data from 855 high-grade glioma cases and 1,160 controls from 4 geographic regions of the United States during 1997-2008 were analyzed for interactions between allergy and smoking histories and inherited variants in 5 established glioma risk regions: 5p15.3 (TERT),...

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Identifiers

PMID: 21742680
DOI: 10.1093/aje/kwr124
PMCID: PMC3202152

Genes

DDX6
PHLDB1
RTEL1
TERT

Provenance

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