Article
Differential CARM1 expression in prostate and colorectal cancers.
BMC cancer - 13 May 2010
Kim Young-Rang, Lee Byung Kook, Park Ra-Young, Nguyen Nguyen Thi Xuan, Bae Jeong A, Kwon Dong Deuk, Jung Chaeyong
Abstract excerpt
BACKGROUND: Coactivator-associated arginine methyltransferase 1 (CARM1) functions as a transcriptional coactivator of androgen receptor (AR)-mediated signaling. Correspondingly, overexpression of CARM1 has been associated with the development of prostate cancer (PCa) and its progression to androgen-independent PCa. In our preliminary study, however, the promoting effects of CARM1, with regard to...
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