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Article

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.

Nature genetics - 1 Jun 2010

Kochi Yuta, Okada Yukinori, Suzuki Akari, Ikari Katsunori, Terao Chikashi, Takahashi Atsushi, Yamazaki Keiko, Hosono Naoya, Myouzen Keiko, Tsunoda Tatsuhiko, Kamatani Naoyuki, Furuichi Tatsuya, Ikegawa Shiro, Ohmura Koichiro, Mimori Tsuneyo, Matsuda Fumihiko, Iwamoto Takuji, Momohara Shigeki, Yamanaka Hisashi, Yamada Ryo, Kubo Michiaki, Nakamura Yusuke, Yamamoto Kazuhiko

Abstract excerpt

Rheumatoid arthritis is a common autoimmune disease with a complex genetic etiology. Here, through a genome-wide association study of rheumatoid arthritis, we identified a polymorphism in CCR6, the gene encoding chemokine (C-C motif) receptor 6 (a surface marker for Th17 cells) at 6q27, that was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Genetic

Share to Regulatory Elements, Transcriptional

Share to T-cell and B-cell Immunology

Source

Identifiers

PMID: 20453841
DOI: 10.1038/ng.583

Genes

CCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20453841-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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