Article
Analysis of a genome-wide association study-linked locus (CCR6) in Asian rheumatoid arthritis.
DNA and cell biology - 1 Apr 2012
Teng Esther, Leong Khai Pang, Li Hui Hua, Thong Bernard, Koh Ee Tzun, Loi Pooi Ling, Zhao Yi, Tan Eng King
Abstract excerpt
A genome-wide association study in Japan identified the C-C chemokine receptor type 6 gene (CCR6) as associated with rheumatoid arthritis (RA). This finding has not been validated in other Asian populations. A case-control study involving 996 subjects, comprising 440 controls and 556 RA patients, was done to determine their anticyclic citrullinated peptide (anti-CCP) antibody status and CCR6 polymorphism...
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