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Article

The incidence of acute graft-versus-host disease increases with Candida colonization depending the dectin-1 gene status.

Clinical immunology (Orlando, Fla.) - 1 Aug 2010

van der Velden Walter J F M, Plantinga Theo S, Feuth Ton, Donnelly J Peter, Netea Mihai G, Blijlevens Nicole M A

Abstract excerpt

Dectin-1 plays an important role in antifungal immunity. The dectin-1 Y238X polymorphism, which results in decreased Th17 responses, is associated with increased Candida colonization of stem cell transplantation (SCT) recipients. In this study we found no impact of the polymorphism on the inciden...

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Source

Identifiers

PMID: 20452827
DOI: 10.1016/j.clim.2010.04.007

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SCT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20452827-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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The incidence of acute graft-versus-host disease increases with Candida colonization depending the dectin-1 gene status.PMID 20452827Read ↗

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Role of the Mycobiome in Human Acute Graft-versus-Host DiseaseSemantic proximity Read ↗

Early Stop Polymorphism in Human DECTIN‐1 Is Associated with Increased <i>Candida</i> Colonization in Hematopoietic Stem Cell Transplant RecipientsSemantic proximity Read ↗

The Y238X stop codon polymorphism in the human β-glucan receptor dectin-1 and susceptibility to invasive aspergillosis.Semantic proximity Read ↗

Innate immune mechanisms for recognition and uptake of Candida species.Semantic proximity Read ↗

Dectin-1: a role in antifungal defense and consequences of genetic polymorphisms in humansSemantic proximity Read ↗

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