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Article

The emerging pathogenic and therapeutic importance of the anaplastic lymphoma kinase gene.

European journal of cancer (Oxford, England : 1990) - 1 Sept 2010

Kelleher Fergal C, McDermott Ray

Abstract excerpt

The anaplastic lymphoma kinase gene (ALK) is a gene on chromosome 2p23 that has expression restricted to the brain, testis and small intestine but is not expressed in normal lymphoid tissue. It has similarity to the insulin receptor subfamily of kinases and is emerging as having increased patholo...

Read the complete abstract on PubMed

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Source

Identifiers

PMID: 20451371
DOI: 10.1016/j.ejca.2010.04.006

Genes

ALK
EML4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20451371-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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