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Article

Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA).

The Journal of biological chemistry - 8 Aug 2003

Ouyang Tao, Bai Ren-Yuan, Bassermann Florian, von Klitzing Christine, Klumpen Silvia, Miething Cornelius, Morris Stephan W, Peschel Christian, Duyster Justus

Abstract excerpt

Anaplastic large-cell lymphoma is a subtype of non-Hodgkin lymphomas characterized by the expression of CD30. More than half of these lymphomas carry a chromosomal translocation t(2;5) leading to expression of the oncogenic tyrosine kinase nucleophosmin-anaplastic lymphoma kinase (NPM-ALK). NPM-ALK is capable of transforming fibroblasts and lymphocytes in vitro and of causing lymphomas in mice. Previously, we and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12748172
DOI: 10.1074/jbc.M300883200

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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