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Article

A comparative phosphoproteomic analysis of a human tumor metastasis model using a label-free quantitative approach.

Electrophoresis - 1 Jun 2010

Xie Xiaolei, Feng Shun, Vuong Huy, Liu Yashu, Goodison Steve, Lubman David M

Abstract excerpt

Alterations in cellular phosphorylation patterns have been implicated in a number of diseases, including cancer, through multiple mechanisms. Herein we present a survey of the phosphorylation profiles of an isogenic pair of human cancer cell lines with opposite metastatic phenotype. Phosphopeptides were enriched from tumor cell lysates with titanium dioxide and zirconium dioxide, and identified with nano-LC-MS/MS...

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Identifiers

PMID: 20446291
DOI: 10.1002/elps.200900752
PMCID: PMC2892005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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