Article
Surveillance for neuraminidase-inhibitor-resistant influenza viruses in Japan, 1996–2007
1 Aug 2008
Abstract excerpt
BACKGROUND: High usage of the neuraminidase inhibitor (NAI) oseltamivir in Japan since 2003 led the Neuraminidase Inhibitor Susceptibility Network to assess the susceptibility of community isolates of influenza viruses to oseltamivir and zanamivir. METHODS: Isolates were tested by the enzyme inhibition assay and by neuraminidase (NA) sequence analysis. RESULTS: Among 1,141 A(H3N2) viruses and 171 type B viruses...
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