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Article

Histone H2B C-terminal helix mediates trans-histone H3K4 methylation independent of H2B ubiquitination.

Molecular and cellular biology - 1 Jul 2010

Chandrasekharan Mahesh B, Huang Fu, Chen Yi-Chun, Sun Zu-Wen

Abstract excerpt

The trans-histone regulatory cross talk between H2BK123 ubiquitination (H2Bub1) and H3K4 and H3K79 methylation is not fully understood. In this study, we report that the residues arginine 119 and threonine 122 in the H2B C-terminal helix are important for transcription and cell growth and play a...

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Identifiers

PMID: 20439497
DOI: 10.1128/MCB.01008-09
PMCID: PMC2897581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20439497-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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