Article
Epithelial-mesenchymal transition abolishes the susceptibility of polarized epithelial cell lines to measles virus.
The Journal of biological chemistry - 2 Jul 2010
Shirogane Yuta, Takeda Makoto, Tahara Maino, Ikegame Satoshi, Nakamura Takanori, Yanagi Yusuke
Abstract excerpt
Measles virus (MV), an enveloped negative-strand RNA virus, remains a major cause of morbidity and mortality in developing countries. MV predominantly infects immune cells by using signaling lymphocyte activation molecule (SLAM; also called CD150) as a receptor, but it also infects polarized epithelial cells, forming tight junctions in a SLAM-independent manner. Although the ability of MV to infect polarized...
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