Article
Mechanism of CD150 (SLAM) down regulation from the host cell surface by measles virus hemagglutinin protein.
Journal of virology - 1 Sept 2004
Welstead G Grant, Hsu Eric C, Iorio Caterina, Bolotin Shelly, Richardson Christopher D
Abstract excerpt
Measles virus has been reported to enter host cells via either of two cellular receptors, CD46 and CD150 (SLAM). CD46 is found on most cells of higher primates, while SLAM is expressed on activated B, T, and dendritic cells and is an important regulatory molecule of the immune system. Previous reports have shown that measles virus can down regulate expression of its two cellular receptors on the host cell surface...
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