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Article

Killing of non-replicating Mycobacterium tuberculosis by 8-hydroxyquinoline.

The Journal of antimicrobial chemotherapy - 1 Jul 2010

Darby Crystal M, Nathan Carl F

Abstract excerpt

OBJECTIVES: To determine the effect of 8-hydroxyquinoline (8HQ) on non-replicating Mycobacterium tuberculosis (Mtb) in comparison with its reported effect on replicating Mtb. METHODS: The MIC of 8HQ for replicating H37Rv Mtb was determined by microdilution in 7H9 broth. Bactericidal activity was determined by exposing H37Rv Mtb to 8HQ for 4 days under conditions that otherwise allowed exponential replication (20%...

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Identifiers

PMID: 20435781
DOI: 10.1093/jac/dkq145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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