Article
Influence of the serotonin transporter gene polymorphism, cannabis and childhood sexual abuse on phenotype of bipolar disorder: a preliminary study.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Oct 2010
De Pradier M, Gorwood P, Beaufils B, Adès J, Dubertret C
Abstract excerpt
OBJECTIVE: The gene coding for the 5-HT transporter (5-HTT) is considered as a candidate gene for bipolar disorder, either as a "vulnerability" or as a "modifying the phenotype" gene. Psychotic symptoms occur at least once in one bipolar patient out of two, the relevant risk factors being insufficiently understood. The gene × environment interaction approach offers the opportunity to disentangle the latter,...
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