Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The interaction between serotonin receptor 2A and catechol-O-methyltransferase gene polymorphisms is associated with the novelty-seeking subscale impulsiveness.

Psychiatric genetics - 1 Dec 2010

Salo Johanna, Pulkki-Råback Laura, Hintsanen Mirka, Lehtimäki Terho, Keltikangas-Järvinen Liisa

Abstract excerpt

OBJECTIVE: Novelty seeking is a trait that has been consistently associated with problem behaviours. There is evidence for heritability of novelty seeking, but the molecular genetic basis of the trait is still widely unclear. METHODS: The interaction between polymorphisms of catechol-O-methyltransferase (COMT) and serotonin receptor 2A genes was examined in relation to novelty seeking and its different subscales...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Exploratory Behavior

Share to Impulsive Behavior

Share to Receptor, Serotonin, 5-HT2A

Share to Young Adult

Source

Identifiers

PMID: 20431430
DOI: 10.1097/YPG.0b013e32833a212f

Genes

COMT

Variants

rs4680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The interaction between serotonin receptor 2A and catechol-O-methyltransferase gene polymorphisms is associated with the novelty-seeking subscale impulsiveness.PMID 20431430Read ↗

Association between the type 4 dopamine receptor gene polymorphism and novelty seeking.Semantic proximity Read ↗

Sex moderates the association between the COMT Val158Met single-nucleotide polymorphism and disorderliness facet of novelty seeking.Semantic proximity Read ↗

The COMT Val158Met polymorphism is associated with novelty seeking in Czech methamphetamine abusers: preliminary results.Semantic proximity Read ↗

Investigation of 17 candidate genes for personality traits confirms effects of the HTR2A gene on novelty seeking.Semantic proximity Read ↗

Association between Novelty Seeking of opiate-dependent patients and the catechol-O-methyltransferase Val(158)Met polymorphism.Semantic proximity Read ↗

Association study of catechol-O-methyltransferase gene and dopamine D4 receptor gene polymorphisms and personality traits in healthy young chinese females.Semantic proximity Read ↗

Association of the functional catechol-O-methyltransferase VAL158MET polymorphism with the personality trait of extraversion.Semantic proximity Read ↗

Association Between the rs4680 Polymorphism of the COMT Gene and Personality Traits among Combat Sports AthletesSemantic proximity Read ↗

Genetics of impulsive behaviour.Semantic proximity Read ↗

The association between the catechol-O-methyltransferase Val108/158Met polymorphism and hyperactive-impulsive and inattentive symptoms in youth.Semantic proximity Read ↗

Why do young women smoke? VII COMT as a risk modifying gene for Nicotine dependence - role of gene-gene interaction, personality, and environmental factors.Semantic proximity Read ↗

Relationship between dopamine system genes and extraversion and novelty seeking.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.