Replication of an association of a common variant in the Reelin gene (RELN) with schizophrenia in Ashkenazi Jewish women.

doi:10.1097/YPG.0b013e32833a220b

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Article

Replication of an association of a common variant in the Reelin gene (RELN) with schizophrenia in Ashkenazi Jewish women.

Psychiatric genetics - 1 Aug 2010

Liu Yaping, Chen Pei-Lung, McGrath John, Wolyniec Paula, Fallin Daniele, Nestadt Gerald, Liang Kung-Yee, Pulver Ann, Valle David, Avramopoulos Dimitrios

Abstract excerpt

A single nucleotide polymorphism (rs7341475) in RELN has recently been shown to be associated with schizophrenia (SZ) in an Ashkenazi Jewish (AJ) case--control study specifically in women by Shifman et al. We have replicated this association in women in another large independent Ashkenazi Jewish collection (721 cases, 259 female; 1455 controls, 834 female) and confirmed that it applies to both SZ and...

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Identifiers

PMID: 20431428
DOI: 10.1097/YPG.0b013e32833a220b
PMCID: PMC2901865

Genes

RELN

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