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Article

Single PCR multiplex SNaPshot reaction for detection of eleven blood group nucleotide polymorphisms: optimization, validation, and one year of routine clinical use.

The Journal of molecular diagnostics : JMD - 1 Jul 2010

Di Cristofaro Julie, Silvy Monique, Chiaroni Jacques, Bailly Pascal

Abstract excerpt

Hemagglutination-based assays have several clinical shortcomings. To overcome this difficulty, we have developed a multiplex-PCR SNaPshot assay adapted to the Southern French population, which includes individuals from sub-Saharan Africa and the Comoros archipelago. Single nucleotide polymorphisms (SNPs) associated with clinically relevant blood antigens as well as with null phenotypes were profiled (i.e., K/k,...

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Identifiers

PMID: 20431033
DOI: 10.2353/jmoldx.2010.090222
PMCID: PMC2893629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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