Article
Anaphylaxis and mast cell disease: what is the risk?
Current allergy and asthma reports - 1 Jan 2010
Akin Cem
Abstract excerpt
Mastocytosis is a proliferative disorder of the hematopoietic mast cell progenitor that results from expansion of a clone carrying the D816V c-kit mutation. Based on the dramatic increase in incidence of anaphylaxis in patients with mastocytosis, recent studies analyzed the presence of clonal mast cell markers, including D816V c-kit mutation, in patients with recurrent IgE- and non-IgE-mediated anaphylaxis. These...
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