Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The therapeutic potential of microRNA modulation.

Discovery medicine - 1 Apr 2010

Jackson Aimee, Linsley Peter S

Abstract excerpt

microRNAs are endogenous small non-coding RNAs that regulate gene expression by interfering with translation or stability of target transcripts. The importance and varied functions of microRNAs are illustrated by the diverse phenotypes, including disease, that arise when microRNAs are mutated or improperly expressed. The association of microRNA dysfunction with disease phenotypes has given rise to the idea that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease
Share to MicroRNAs
Share to Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20423675

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The therapeutic potential of microRNA modulation.PMID 20423675Read ↗

The function of MicroRNA in hepatitis B virus-related liver diseases: from Dim to BrightSemantic proximity Read ↗

MicroRNAs in liver disease.Semantic proximity Read ↗

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA.Semantic proximity Read ↗

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus InfectionSemantic proximity Read ↗

MicroRNA-122 Regulation of HCV Infections: Insights from Studies of miR-122-Independent ReplicationSemantic proximity Read ↗

Emerging role of microRNAs in liver diseasesSemantic proximity Read ↗

Unraveling the Mysterious Interactions Between Hepatitis C Virus RNA and Liver-Specific MicroRNA-122Semantic proximity Read ↗

The Biological Limits of microRNA Therapeutics: Lessons from Preclinical and Clinical StudiesSemantic proximity Read ↗

MicroRNAs, transforming growth factor beta-1, and tissue fibrosis.Semantic proximity Read ↗

MicroRNAs, Hepatitis C Virus, and HCV/HIV-1 Co-Infection: New Insights in Pathogenesis and TherapySemantic proximity Read ↗

Hepatitis C virus' Achilles' heel--dependence on liver-specific microRNA miR-122.Semantic proximity Read ↗

Activation of hepatitis c virus translation by a liver-specific microRNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.