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Article

MicroRNAs, transforming growth factor beta-1, and tissue fibrosis.

The Journal of pathology - 1 Jan 2013

Bowen Timothy, Jenkins Robert H, Fraser Donald J

Abstract excerpt

MicroRNAs are short noncoding RNA regulators that repress synthesis of their targets post-transcriptionally. On average, each microRNA is estimated to regulate several hundred protein-coding genes, and about 60% of proteins are thought to be regulated by microRNAs in total. A subset of these genes, including the key profibrotic cytokine transforming growth factor beta-1 (TGF-β1), exhibits particularly strong...

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Identifiers

PMID: 23042530
DOI: 10.1002/path.4119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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