Article
Cardiovascular events are not associated with MTHFR polymorphisms, but are associated with methotrexate use and traditional risk factors in US veterans with rheumatoid arthritis.
The Journal of rheumatology - 1 Jun 2013
Davis Lisa A, Cannon Grant W, Pointer Lauren F, Haverhals Leah M, Wolff Roger K, Mikuls Ted R, Reimold Andreas M, Kerr Gail S, Richards J Steuart, Johnson Dannette S, Valuck Robert, Prochazka Allan, Caplan Liron
Abstract excerpt
OBJECTIVE: C677T and A1298C polymorphisms in the enzyme methylenetetrahydrofolate reductase (MTHFR) have been associated with increased cardiovascular (CV) events in non-rheumatoid arthritis (RA) populations. We investigated potential associations of MTHFR polymorphisms and use of methotrexate (M...
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