Article
A ghrelin gene variant may predict crossover rate from restricting-type anorexia nervosa to other phenotypes of eating disorders: a retrospective survival analysis.
Psychiatric genetics - 1 Aug 2010
Ando Tetsuya, Komaki Gen, Nishimura Hiroki, Naruo Tetsuro, Okabe Kenjiro, Kawai Keisuke, Takii Masato, Oka Takakazu, Kodama Naoki, Nakamoto Chiemi, Ishikawa Toshio, Suzuki-Hotta Mari, Minatozaki Kazunori, Yamaguchi Chikara, Nishizono-Maher Aya, Kono Masaki, Kajiwara Sohei, Suematsu Hiroyuki, Tomita Yuichiro, Ebana Shoichi, Okamoto Yuri, Nagata Katsutaro, Nakai Yoshikatsu, Koide Masanori, Kobayashi Nobuyuki, Kurokawa Nobuo, Nagata Toshihiko, Kiriike Nobuo, Takenaka Yoshito, Nagamine Kiyohide, Ookuma Kazuyoshi, Murata Shiho
Abstract excerpt
BACKGROUND: Patients with anorexia nervosa restricting type (AN-R) often develop bulimic symptoms and crossover to AN-binge eating/purging type (AN-BP), or to bulimia nervosa (BN). We have reported earlier that genetic variants of an orexigenic peptide ghrelin are associated with BN. Here, the relationship between a ghrelin gene variant and the rate of change from AN-R to other phenotypes of eating disorders...
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