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Article

Embryonated Eggs as an Alternative Infection Model To InvestigateAspergillus fumigatusVirulence

27 Apr 2010

Abstract excerpt

Infection models are essential tools for studying microbial pathogenesis. Murine models are considered the "gold standard" for studying in vivo infections caused by Aspergillus species, such as A. fumigatus. Recently developed molecular protocols allow rapid construction of high numbers of fungal deletion mutants, and alternative infection models based on cell culture or invertebrates are widely used for...

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PMID: 20421382
DOI: 10.1128/iai.00268-10

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