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Article

Mutations in VEGFA are associated with congenital left ventricular outflow tract obstruction.

Biochemical and biophysical research communications - 28 May 2010

Zhao Wu, Wang Jian, Shen Jie, Sun Kun, Zhu Junxue, Yu Tingting, Ji Wei, Chen Yiwei, Fu Qihua, Li Fen

Abstract excerpt

Left ventricular outflow tract obstruction (LVOTO) comprises a spectrum of stenotic lesions. Previous studies have shown that the vascular endothelial growth factor (VEGF) signaling system plays a critical role in cardiac cushion formation, vasculogenesis, and angiogenesis. We hypothesize that VEGFA may be a potential candidate gene associated with the spectrum of LVOTO lesions. However, it remains unclear...

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Source

Identifiers

PMID: 20420808
DOI: 10.1016/j.bbrc.2010.04.124

Genes

VEGFA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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