Article
Potential involvement of vascular endothelial growth factor in pathophysiology of Turner syndrome.
Medical hypotheses - 1 Jan 2005
Brandenburg H, Steegers E A P, Gittenberger-de Groot A C
Abstract excerpt
Vascular endothelial growth factor (VEGF) is a specific growth factor for endothelium but plays also a role in the signaling involved in embryonic endocardial-to-mesenchymal transformation of the endocardial cushions. Furthermore, VEGF is the major vascular permeability factor in both fetal and postnatal life. Overexpression of VEGF during fetal life is associated with fetal hydrops and abnormal endocardial...
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